Endocytic uptake of monomeric amyloid-β peptides is clathrin- and dynamin-independent and results in selective accumulation of Aβ(1–42) compared to Aβ(1–40)

$ 17.50

4.8 (566) In stock

Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

Misfolded protein oligomers: mechanisms of formation, cytotoxic effects, and pharmacological approaches against protein misfolding diseases, Molecular Neurodegeneration

IJMS, Free Full-Text

Alzheimer's disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

Human amyloid-β enriched extracts: evaluation of in vitro and in vivo internalization and molecular characterization, Alzheimer's Research & Therapy

Evidence for aggregation-independent, PrPC-mediated Aβ cellular internalization. - Abstract - Europe PMC

Biomolecules, Free Full-Text

The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer's disease, Acta Neuropathologica Communications

IJMS, Free Full-Text

Uptake of Aβ by OATPs might be a new pathophysiological mechanism of Alzheimer disease, BMC Neuroscience