Comparison of ALK and LTK structure and sequence. (A) Schematic of ALK

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Cryo-EM structure of the heterotetrameric ALK-ECRABR–ALKAL2 complex a

Domain structure of human ALK and human LTK The N-terminal region of

LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity

Structural basis of cytokine-mediated activation of ALK family receptors

Frontiers Current status and challenges of immunotherapy in ALK rearranged NSCLC

Role and targeting of anaplastic lymphoma kinase in cancer, Molecular Cancer

The function and therapeutic targeting of anaplastic lymphoma kinase (ALK) in non-small cell lung cancer (NSCLC), Molecular Cancer

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LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity

FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase

Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugs