A protein with a dual role: Both repair and mutation

Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 involving scientists from CNRS, ENS-PSL and supported by Inserm has demonstrated and described this phenomenon. Better understanding of mutations opens up prospects in the fight against resistance to antibiotics and anti-cancer therapies. This study was published in PNAS on 5 April 2021.

Double-Strand DNA Breaks Learn Science at Scitable

Sting and p53 DNA repair pathways are compromised in Alzheimer's disease

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis - ScienceDirect

Ku (Protein) - an overview

Elledge Lab

Newsroom

Unravelling roles of error-prone DNA polymerases in shaping cancer genomes

Newsroom

Frontiers DNA Repair Pathways in Cancer Therapy and Resistance

CRISPR-Cas12a induced DNA double-strand breaks are repaired by multiple pathways with different mutation profiles in Magnaporthe oryzae

Newsroom

H3.1K27me1 loss confers Arabidopsis resistance to Geminivirus by sequestering DNA repair proteins onto host genome

DNA repair - Wikipedia

18V ONE+ DUAL FUNCTION DIGITAL INFLATOR/DEFLATOR - RYOBI Tools

Dual function materials for CO2 capture and conversion using

43 Amber/White Dual Function LED Bar – Cali Raised LED

HART 20-Volt Cordless Dual Function Digital Inflator (Battery Not Included)

Monoprice Blackbird 8K Dual Function Splitter/Switch (1x2 Splitter or 2x1 Switch), 8K@60, 4K@120, 40Gbps, HDR, HDMI 2.1, HDCP 2.3, EDID