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Transcribed ultraconserved regions (T-UCRs) associated with cancer

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Download scientific diagram | -Transcribed ultraconserved regions (T-UCRs) associated with cancer cell processes. They mostly affect cell proliferation, migration/invasion and apoptosis in distinct tumor types. Green arrows meaning promotion and red arrows meaning suppression of the mechanisms. Created with BioRender.com from publication: Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers | The ultraconserved regions (UCRs) are 481 genomic elements, longer than 200 bp, 100% conserved in human, mouse, and rat genomes. Usually, coding regions are more conserved, but more than 80% of UCRs are either intergenic or intronic, and many of them produce long non-coding | Transcribing, Prognosis and Regulations | ResearchGate, the professional network for scientists.

Transcribed ultraconserved regions (T-UCRs) associated with cancer

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Overexpression of the transcribed ultraconserved region Uc.138 accelerates colon cancer progression

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