JCM, Free Full-Text
5 (519) In stock
Down syndrome (DS) is a form of accelerated aging, and people with DS are highly prone to aging-related conditions that include vascular and neurological disorders. Due to the overexpression of several genes on Chromosome 21, for example genes encoding amyloid precursor protein (APP), superoxide dismutase (SOD), and some of the interferon receptors, those with DS exhibit significant accumulation of amyloid, phospho-tau, oxidative stress, neuronal loss, and neuroinflammation in the brain as they age. In this review, we will summarize the major strides in this research field that have been made in the last few decades, as well as discuss where we are now, and which research areas are considered essential for the field in the future. We examine the scientific history of DS bridging these milestones in research to current efforts in the field. We extrapolate on comorbidities associated with this phenotype and highlight clinical networks in the USA and Europe pursuing clinical research, concluding with funding efforts and recent recommendations to the NIH regarding DS research.
JCM, Free Full-Text, buona spray sol nasal
JCM Free Full-Text Pathophysiology And Clinical Management, 56% OFF
Jcm Font: Download for Free, Online
JCM, Free Full-Text
JCM, Free Full-Text, rubinstein taybi genereviews
JCM, Free Full-Text, niemann pick disease
Images
JCM, Free Full-Text
Continuum Health on X: JCM, Free Full-Text
Mindy Gridley - Talent Acquisition Coordinator - Heartland Retirement Group
2023 Honda® FourTrax Foreman 4x4 EPS
Allegory of Beauty & Uncertainty, an art print by Liz Gridley - INPRNT
- Ethika Cloud Nine Boy Shorts
- Mattel's latest lineup of diverse dolls includes a Barbie with hearing aids - Good Morning America
- Victoria's Secret - Bras, Facebook Marketplace
- Men's Number 2 Micro Crew Midweight Hiking Sock
- CRZ YOGA Matte Faux Leather Leggings for Women 25''/28'' - High Waisted Ocean Bue Plain, 28 inches, XX-Small купить от 7331 рублей в интернет-магазине из США с доставкой в Россию
- Lace bralette with back detail - Black - Sz. 85E-115H - Zizzifashion